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Potentiometric analysis of chloride polyhexamethyleneguanide pK-spectroscopy

Tetiana S. Chmilenko, Ekaterina A. Chebrova, Fedor A. Chmilenko


The mathematical analysis of data of titration of chloride polyhexamethyleneguanide (PGMG) containing repeating functional group, capable to a deprotonation carried out. For the characteristic of interparticle cooperation in system water - PGMG the method of pK-spectroscopy is offered for using. The metod based on the use of linear regression analysis with restrictions on the non-negative solutions. The experimental curve of electrometric titration of PGMG is received and transformed to function of distribution of ionogenic groups of titration object on sizes рК acid ionization (pK-spectrum). The method of pK-spectroscopy the possibility of using to predict the spatial structure and conformational transitions of polycations. The interrelation of constants of dissociations of PGMG and transition a globule-ball in water solutions is studied. 


potentiometer method; pK-spectrum; regression analysis


Garmash, A. V. Potentiometric analysis of polyelectrolytes by pK-spectroscopy using linear regression. Zhurn. Anal. Khim., 1998, vol. 53, no 4, p. 411-417.

Leuenberger, B., Schindler, P. W. Application of integral pK-spectrometry to the titration curve of ulvic acid. Anal. Chem., 1986, vol. 58, р. 1471-1474.

Cholin, U. V., Merniy, S. A. Description equilibria involving macromolecular ligands with a model of a continuous distribution of the equilibrium constants. Ukr. Khim. Zhurn., 1991, no. 7, p. 688-691.

Varshal, G. М. , Bugaevsky, А. А., Cholin, U. V. Modeling of equilibria in solutions of fulvic acids in natural waters. Khim. Tekhnol. Vody, 1990, vol. 12, no. 11, p. 979-983.

Garmash, A. V., Vorobyova, О. N. Validation results in potentiometric analysis polyelectrolyte pK spectroscopy methods. Zhurn. Anal. Khim., 1998, vol. 53, no. 3, p. 258-264.

Sobanov, A. A. Metodicheskie ukazaniya k kursu vyisokomolekulyarnyie soedineniya. Kazan: Kazan State University, 2007, 35 p.

Lawson, C., Henson, R. Chislennoe reshenie zadach metoda naimenshih kvadratov, Moscow: Nauka, 1986, 230 p.

Kudrev, A. G. Calculation of association constants in solution with polynucleotides. Vysokomol. Soedin., 2000, vol. 42, no. 5, p. 803-810.

Albert, A., Sergeant, Е. Konstantyi ionizatsii kislot i osnovaniy, Moscow: Khimiya, 1964., 179 p.

Garmash, A. V., Ustimova, I. V., Kudryavtsev, A. V. Potentiometric analysis of complex systems by protolytic pK spectroscopy using linear regression. Zhurn. Anal. Khim., 1998, vol. 53, no. 3, p. 241-248.

Mchedlov-Petrosyan, N. O. Differentsirovanie silyi organicheskih kislot v istinnyih i organizovannyih rastvorah, Kharkov: Publishing house of the V.N. Karazin Kharkov National University, 2004, 326 p.

Fukushima, M., Tanaka, S., Hasebe, K. Interpretation of the acid-base equilibrium of humic acid by a continuous pK distribution and electrostatic model. Anal. Chim. Acta. 1995, vol. 302, p. 365-373.

Shamrikova, E. V., Ryazanov, M. A., Vanchikova, E. V. Acid–base properties of water-soluble organic matter of forest soils, studied by the pK-spectroscopy method. Chemosphere, 2006, no. 65, p. 1426-1431.



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