INTEGRATION OF ARTIFICIAL INTELLIGENCE INTO THE TEACHING OF CHEMICAL TECHNOLOGY IN HIGHER EDUCATION: A SYSTEMATIC REVIEW
DOI:
https://doi.org/10.15421/jchemtech.v34i1.344737Keywords:
artificial intelligence, chemical technology, digital twins, machine learning, course projecting, modeling, optimization, adaptive learningAbstract
This article analyzes the strategic importance and practical aspects of incorporating artificial intelligence (AI) technologies into the training of chemical engineering students at higher education institutions. The study is based on a systematic scoping review of scientific publications from 2021 to 2025. Based on these sources, the author identifies six major applications of AI in education: modeling and optimizing technological processes with machine learning, using digital twins and augmented reality, incorporating generative AI into project-based learning, applying adaptive learning systems, enabling automated assessment, supporting academic integrity. The article provides empirical evidence illustrating the effectiveness of these approaches. Researchers report that machine learning methods can increase reactor design productivity by up to 60 %, and over 90 % of students positively evaluate the use of generative AI in project-based learning. The analysis emphasizes the role of digital twins in creating highly realistic and safe environments for developing professional skills, including those necessary for hazardous industrial settings. The author also examines how Ukrainian universities adopt AI amid wartime conditions and restricted access to in-person learning. Virtual laboratories and digital simulators help students compensate for limited access to specialized equipment. The article offers practical recommendations for educators, such as expanding computational infrastructure, utilizing digital simulators, and fostering collaboration with industry professionals. The author also shares their personal experience teaching with AI-driven adaptive learning. The conclusion emphasizes that, while AI can modernize chemical engineering education, it cannot replace critical thinking. Since AI-generated content often contains inaccuracies, students and instructors must carefully verify information. To reduce the risk of academic dishonesty, the author recommends increasing the proportion of in-person and oral assessments.
References
Keith, M., Keiller, E., Windows-Yule, Ch., Kings, I., Robbins, Ph. (2025). Harnessing generative AI in chemical engineering education: Implementation and evaluation of the large language model ChatGPT v3.5. Education for Chemical Engineers, 50, 1–12. https://doi.org/10.1016/j.ece.2025.01.002.
Ramos, B., Condotta, R. (2024). Enhancing Learning and Collaboration in a Unit Operations Course: Using AI as a Catalyst to Create Engaging Problem-Based Learning Scenarios. Journal of Chemical Education, 101(8), 3246–3254. https://doi.org/10.1021/acs.jchemed.4c00244.
University of Tulsa. (2025). UTulsa’s chemical engineering program integrates AI into every course. https://utulsa.edu/news/utulsas-chemical-engineering-program-integrates-ai-into-every-course/.
Carnegie Mellon University. (2024). Master’s in Artificial Intelligence Engineering-Chemical Engineering. https://www.cheme.engineering.cmu.edu/education/graduate-programs/masters/aie-che.html.
Supan, K. (2024). Using artificial intelligence case studies in a thermodynamics course. ASEE Annual Conference Proceedings. https://peer.asee.org/using-artificial-intelligence-case-studies-in-a-thermodynamics-course.pdf.
Ghasem, N. (2025). The significance of artificial intelligence and machine learning in contemporary chemical engineering curriculum. Cogent Engineering, 12(1), 2560057. https://doi.org/10.1080/2331186X.2025.2560057.
Bilgin, B. (2025). Generative AI in chemical engineering education: Rebuilding courses and students’ perception of AI. ASEE Annual Conference, Paper ID 2025-123. http://doi.org/10.18260/1-2--56640.
Shin, J., Son, J. (2024). Education and Training Using Digital Twin in Hazardous Chemical Manufacturing Plants. In: Tareq Ahram and Waldemar Karwowski (eds) Human Factors in Design, Engineering, and Computing. AHFE (2024) International Conference. AHFE Open Access, 59. http://doi.org/10.54941/ahfe1005762.
Galeazzi, A., Marenghi, P., Duo, L., Galardo, M., Rota, R., Sancassani, S., Manenti, F. (2024). Virtual reality and digital twins for enhanced learning in chemical engineering. Computer Aided Chemical Engineering, 53, 3535–3540. https://doi.org/10.1016/B978-0-443-28824-1.50590-1.
Savage, T., Basha. N., McDonough, J., Krassowski, J., Matar, O., del Rio Chanona, E. A. (2024). Machine learning-assisted discovery of flow reactor designs. Nature Chemical Engineering, 1, 522–531. https://doi.org/10.1038/s44286-024-00099-1.
Woinaroschy, A. (2021). Interdisciplinarity: Artificial intelligence and chemical engineering. Journal of Engineering Studies and Innovation, 6(4), 473–480.
Rebello, C. M., Nogueira, I. B. R. (2025). Digital twins in chemical engineering: An integrated framework for identification, implementation, online learning, and uncertainty assessment. Computers & Chemical Engineering, 200, 109178. https://doi.org/10.1016/j.compchemeng.2025.109178
Yuriev, E., Wink, D. J., Holme, T. A. (2024). The dawn of generative artificial intelligence in chemistry education. Journal of Chemical Education, 101(8), 2957–2959. https://doi.org/10.1021/acs.jchemed.4c00836.
Wu, M., Boase, N. R. B. (2023). An artificial intelligence course for chemical engineers. Education for Chemical Engineers, 45, 141–150. https://doi.org/10.1016/j.ece.2023.09.004.
Rudniy, A. (2024). Artificial intelligence for automated scoring and feedback in chemistry courses. Journal of Writing Analytics, 7(1), 49–75. https://doi.org/10.37514/JWA-J.2024.7.1.02.
Vincent-Ruz, P., Boase, N. R. B. (2022). Activating discipline specific thinking with adaptive learning. PLOS ONE, 17(11), e0276546. https://doi.org/10.1371/journal.pone.0276086.
Desaire, H., Chua, A. E., Kim, M.-G., Hua, D. (2023). Accurately detecting AI text when ChatGPT is told to write like a chemist. Cell Reports Physical Science, 4(11), 101672. https://doi.org/10.1016/j.xcrp.2023.101672.
Perkins, M. (2023). Academic integrity considerations of AI large language models in the post-pandemic era. Journal of University Teaching & Learning Practice, 20(2), 1–18. https://doi.org/10.53761/1.20.02.07.
Araújo, J. L., Saúde, I. (2024). Can ChatGPT enhance chemistry laboratory teaching? Using prompt engineering to enable AI in generating laboratory activities. Journal of Chemical Education, 101(5), 1858–1864. https://doi.org/10.1021/acs.jchemed.3c00745.
Chiu, W.-K. (2021). Pedagogy of emerging technologies in chemical education during the era of digitalization and AI: A systematic review. Education Sciences, 11(11), 709–732. https://doi.org/10.3390/educsci11110709.
Pasichnyi, R., Serhieiev, V., Shevchenko, S., Petrukha, N., Hryvnak, B. (2024). Digital transformation of higher education as a driver of Ukraine’s integration. Brazilian Journal of Technology and Society, 17(4), 232–245. https://dx.doi.org/10.14571/brajets.v17.nse4.2024.
Eurydice. (2025). Ukraine: Digital transformation of education as a strategic path to resilience. Eurydice News, 27. https://eurydice.eacea.ec.europa.eu/news/ukraine-digital-transformation-education-strategic-path-resilience-and-innovation.
Kudria, O., Skovronskyi, B., Marushchak, O., Honcharova, N., Sipii, V. (2024). The Role of Innovative Techniques in Development of STEM-education in Ukraine. ACADEMIA, 35-36. 132–155. https://doi.org/10.26220/aca.5006/
Masterchemoinfo. (2025). ChEMoinformaticsPlus: the Erasmus Mundus Master degree in Chemoinformatics across Europe and beyond. https://masterchemoinfo.u-strasbg.fr.
University of Michigan ChE. (2025). Accelerating innovation with machine learning. Retrieved from https://che.engin.umich.edu/2025/02/24/accelerating-innovation-with-machine-learning/.
Bělohlav, V., Jirout, T., Malecky, M., Herink, T. (2024). Effective application of operator training simulator in experiential education. Computer Applications in Engineering Education, 32(4), e22743. https://doi.org/10.1002/cae.22743 .
Zhou, Z., Oveissi, F., Langrish, T. (2024). Applications of augmented reality (AR) in chemical engineering education: Virtual laboratory work demonstration to digital twin development. Computers & Chemical Engineering, 188, 108784. https://doi.org/10.1016/j.compchemeng.2024.108784
Mane, S., Dhote, R. R., Sinha, A., Thirumalaiswamy, R. (2024). Digital twin in the chemical industry: A review. IET Digital Twins, 1(2), 118–130. https://doi.org/10.1049/dgt2.12019.
Zhang, Y., Wang, W., Yang, Q., Tang, X., Ruan, W., Li, Y., Daoerji, S., Zhang, X., Ye, Y., Huang, J., Li, J., Yang, Y., Wu, X., Yang, H., Cao, T. (2024). Promoting digital twin technology application for process industry: A novel generation modelling platform and its implementations. IET Digital Twins, 1(1), 51–74. https://doi.org/10.1049/dgt2.12010 .
ChemCopilot. (2025). Digital Twins and PLM: Creating digital twins of chemical products for lifecycle optimization. https://www.chemcopilot.com/blog/digital-twins-and-plm-lifecycle-optimization.
Tanner, J., Newbery, C. (2022). Digital twins in the chemical process industries. The Chemical Engineer, 29. https://www.thechemicalengineer.com/features/digital-twins-in-the-chemical-process-industries.
Laub, J.-F., Zhang, J., Heyer, M., Lapkin, A. (2025). Automated generation of mechanistic models for chemical processes. ChemRxiv Preprint. https://chemrxiv.org/engage/chemrxiv/article-details/67dd89d681d2151a02545d2c.
DWSIM - Open Source Process Simulator/ URL: https://sourceforge.net/projects/dwsim/
ML.NET. https://dotnet.microsoft.com/en-us/apps/ai/ml-dotnet?utm_source=chatgpt.com/
Akademija ShI dlja osvitjan vid Google. URL: https://google.brandlive.com/AI-Academy-for-University-Teachers-Cohort-2/uk/home/ Data zvernennya 15.11.2025.
Science City: New Opportunities for Business, Science, and Innovation. https://mon.gov.ua/en/news/science-city-novi-mozhlyvosti-dlia-biznesu-nauky-ta-innovatsii/ Data zvernennya 15.11.2025.
Klaster informacijnykh promyslovykh tekhnologhij. https://www.iitc.org.ua/
National Office Erasmus+UA. https://erasmusplus.org.ua/
Podzharsky, M. A., Nesterov, A. M. (2021). Modeling of the technological process of sulfur dioxide oxidation using the CHEMCAD program. Journal of Chemistry and Technologies, 29(4), 576–585. https://doi.org/10.15421/jchemtech.v29i4.244347.
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